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Bio X4 Review

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Bio X4 is a compound that comprises 4 ingredients aimed to help you lose weight via probiotics. This does not really make a good case since there is no evidence that backs up the effectiveness of probiotics and digestive enzyme supplements to weight loss.

The reviews on other sites that are not the official site are very mixed. This could be an indication that if there are any products that have no typical results, this one probably makes it to that list.

Let’s take a look at how effective Bio X4 by Nucific can be for weight loss. As usual, we will just state the facts and let you make the call.

Bio X4 Ingredients

The ingredients in Bio X4 are aimed at helping you control those craves that make you eat unhealthy food. The following are the ingredients that Nucific claims to have added to Bio X4.

  • Caraluma Fimbriata – to suppress appetite.
  • EGCG – found in green tea and thought to boost fat-burning metabolic action.
  • Digestive Enzymes:
    • Amylase – breaks down sugars
    • Lipase – breaks down fats
    • Bromelain – breaks down proteins. It also helps soothe intestinal irritation
  • Probiotics:
    • Lactobacillus acidophilus blend (L. acidophilus, L. rhamnosus, L. planterum) – might improve lipid metabolism (not enough evidence to support this claim)
    • Bifidobacterium blend (B. lactis, B. animalis) – may help some digestive disorders such as irritable bowel syndrome

Bio X4 Claims

The official Nucific site for this product claims that the product can help with the following:
BIO-X4 is specifically designed to flip that situation on its head and help you…

  • Control those cravings that make you overeat
  • Boost your metabolism and burn more fat
  • Get the energy and nutrients you need from the food you eat
  • Feel more confident without gas and bloating after eating

How this is specifically done is explained.

  • The digestive enzymes help break down nutrients from your food in order to take full advantage of those nutrients.
  • Caralluma Fimbriata is known to suppress hunger.
  • EGCG, which is found in green tea, helps support metabolism.
  • The daily recommended dose of three capsules adds up 12 billion colony-forming units (CFUs) to help rebalance the digestive tract.

Basically, the claim is that right after you eat your meal, taking one or two of these pills will help you take better advantage of the nutrients from the food you just ate. The plan is to make your digestive tract operate to the peak of its performance.

Bio X4 Guarantees

Nucific offers what sounds like a very reasonable 90-day money-back guarantee. On their website it says:

Yes. We stand by all of our products. We have an unconditional, 90-day money-back guarantee. If you are not completely satisfied with your order, send it back and we will give you a 100% refund. To begin the process, please call 888-679-5520 Monday – Friday from 5 am to 7 pm PST, as well as weekends 6 am to 4:30 pm PST.

However, I was not able to find any fine print giving important details on how does this refund work. For example, does the guarantee apply to open or unopened bottles? What is the processing fee that will be required? The best option here, if you want to be sure, is to contact Nucific to the numbers specified above.

How Much Does Bio X4 Cost?

One bottle of this supplement with a 30-day supply costs $99.00 when purchased from the official website. Interestingly, if you find it in Amazon, the price is around $60 but from different sellers, none of which appears to be Nucific.

About shipping, it is free for orders greater than $50.

The official site has some special offers to help you buy a 90-day and a 120-day dose:

  • 6 bottles (180-day supply): $487.08
  • 3 bottles (90-day supply): $261.36
  • 1 bottle (30-day supply): $99.00

How to Take Bio X4

The recommended daily dose is pretty simple. Take 1 capsule with a meal, three times a day. You can also take two if you wish but should not exceed six capsules in one day.

Does Bio X4 Work?

As with any other supplement out there, results will depend on every person. For instance, it will probably work wonders on some users but might not work at all in others.

From a purely scientific standpoint, there is no evidence that probiotics actually help with weight loss. There have been some clinical tests but these are either inconclusive or way too scarce. The same goes to digestive enzyme supplements.

The EGCG found in green tea and the Caralluma Fimbriata do have supported evidence on how they help to lose weight. However, we believe that the amounts present are not really adequate to help make some significant loss.

The studies on the effect of probiotics to weight loss are mostly in their initial phase and they do not help back up Nucific’s claim that they will aid in any weight-loss program. Besides this, you must consider that probiotics are bacteria, and adding more to your flora might actually cause more harm than good.

The claims on the work of digestive enzymes are also inconclusive. There is no proof that they actually aid to lose weight.


  • It has ingredients that helps you control your cravings
  • 90-day money-back guarantee


  • Medical claims are not supported by the FDA
  • Only available through the 
  • Expensive
  • Not safe for everyone
  • Results may vary
  • Products that are sold from other stores are fake

Is Bio X4 a Scam, or is it worth the money?

Bio X4 is sold by a reputable company that always lives up to its promises. So, there is no evidence or indication of this being a scam.

Now, about the part of it being worth the money, one 30-day bottle is worth almost $100. This might seem like a lot for many people.

What Are The Side Effects Of Bio X4?

The site claims that the product does not have any side-effects. However, come on! There are always side-effects to any medication or supplement; some are very obvious and others are just rarely seen.

Also, some people might not experience side effects within days while others might experience them the moment they take the first dose. Healthy users are very unlikely to experience any side effect from this product.

But side effects will very likely happen to patients with a weakened immune system or compromising underlying conditions.

Bio X4 Concerns

The concerns regarding Bio X4 reside mostly on the fact that these products have very varied effects on people.

These are some concerns:

  • Customer feedback is not enough to prove its effectiveness.
  • It is not safe for everyone. May have harmful effects if your immune system is not strong enough. One could be introducing bacteria into a body not capable of fighting the excess. This could be dangerous.
  • Any effects of this product can be expected.

Bio X4 Customer Reviews

Reviews from customers are actually pretty varied. We will not take those included on the official website only since those are most likely filtered. However, some positive reviews say.

“After just one week of consistently taking BIO X4 I feel better than before and I’ve noticed quite a few changes in my body… 1. I really do not crave sugar or sweeteners. I can drink my coffee black and feel good about it. 2. My bathroom visits are more consistent and definitely different than before. 3. I feel like I sweat more easily, and burn calories + fat nearly all day, even inside an air-conditioned home.”

“It works! 3months in smaller size less visceral fat, less bloating now the subcutaneous fat is thinning out, can fit in my tight clothes and look hot again. Don’t judge by the scale, judge by looking thinner in the neck, body parts and less bloating. Only had occasional diarrhea, could be more or less depending on the person but each time it happens you get even thinner and cleanse. Buying again, it’s good maintenance once you’re at your desired size.”

Negative reviews were not found on the site and there are reports that the one being sold in Amazon is not the original Nucific product.

Where to Buy Bio X4?

Bio X4 is only available through the Nucific official website. You will not find it anywhere else. As stated above, the ones sold in Amazon are not the original product. Then, someone could be selling the original product on eBay or some other place. Either way, we recommend getting them from Nucific only.

This is where you can safely claim the guarantee.

Final Decision On Bio X4

So we have come to the point where we have to let you be the one who decides if you want to go for this one or not. There are several things that you need to weigh in and I’ll jot them out for you:

  • There is not enough scientific evidence on how probiotics or digestive enzymes can help with weight loss. Studies are inconclusive and scarce. Not enough to blindly accept the producers’ claims.
  • As with most supplements, medical claims are not supported by the FDA. So, the entire product could be just flour in gel tablets, for all you can tell.
  • The product seems to have very varied results. It appears to work on some and not too well on others.
  • So, you are probably thinking, “I can claim the guarantee if it does not work for me.” Fair enough. Just consider this, 90-day money back guarantee seems too good to be true. It does because it probably is. We strongly recommend you call about the terms and conditions of this guarantee. Ask the important questions. Some guarantees apply only to unopened bottles which you have to ship back. Sometimes refunding requires some management fee that you have to pay.

I will not go as far as recommending this product. There definitely are better supplements with more promising reviews.

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